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        Nc2Eye

           A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of pterygium
ncRNA name hsa-miR-221
ncRNA Category miRNA
Disease name pterygium
Species Homo sapiens
Tissues/Cell_line pterygial and normal conjunctival samples; pterygium cell lines (PECs)
Methods immunohistochemistry, RT-PCR, Western blot
Expression pattern up-regulated
Functional description Activation of β-catenin in pterygium may interact with miR-221, resulting in p27Kip1 gene downregulation that influences pterygium pathogenesis.
PubMed ID 25053875
Year 2014
Title MiRNA-221 negatively regulated downstream p27Kip1 gene expression involvement in pterygium pathogenesis.
Drug-related ncRNA NO

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